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French and American quality and safety standards
The Fetal Medicine Unit screens for the following anomalies:
Screening for these anomalies can be performed during the 1st and 2nd trimester fetal check-up, and results are generally available within 24 hours.
We also offer genetic consultations.
The aim of these consultations is to screen for parental risk factors such as hemophilia, cystic fibrosis, fragile X syndrome and a host of other disorders for which one or more genes have been identified.
The Unit can also perform:
- specialized fetal ultrasound and echocardiogram
- specialized biological testing
- prenatal testing for the main trisomies in the maternal blood (non-invasive analysis of fetal DNA in the maternal blood)
- CVS (chorionic villus sampling)
- fetal blood sampling
This combined test assesses the risk of Trisomy 21 (Down syndrome) in the 1st trimester of pregnancy.
If fetal sampling (chorionic villus sampling) is advised:
The 1st trimester prenatal diagnosis can be performed in a half-day.
All exams and consultations (blood test, ultrasound and consultation with a specialist) can be performed in one half-day.
Download our One Day Test brochure
NIPT (Non-Invasive Prenatal Testing for trisomies 13, 18 and 21) is also known as cell-free DNA screening (for trisomies 13, 18 and 21 through cell-free DNA analysis).
NIPT is a rapid, reliable and zero-risk genetic test that screens for the main trisomies (21,13 and 18) that may occur during pregnancy, using a simple maternal blood sample.
This screening method poses no risk for your pregnancy, unlike invasive exams such as chorionic villus sampling or amniocentesis, which have an associated risk – albeit very low at 0.1 to 0.2 percent – of miscarriage.
Starting from the 11th week of pregnancy, for high-risk populatins, NIPT can detect chromosomal disorders with a sensitivity rate greater than 99 percent.
It is therefore not a diagnostic test but a highly sensitive screening test.
Our Fetal Medicine Unit began offering NIPT in January 2013, and has performed more than 10,000 tests to date.
This test screens for abnormalities in chromosomes 21, 13 and 18 with a sensitivity rate greater than 99 percent, even in populations with an intermediate or low risk.
The results are given as follows:
The typical indication for this test is when combined first semester screening (known as the One Day Test) for trisomy 21 shows an intermediate risk, between 1/51 and 1/1000.
As of January 17, 2019, NIPT is covered for this particular indication by Assurance Maladie, the French national health insurance.
NIPT may also be indicated in other circumstances following a genetic counseling consultation, especially if the patient has personal or family antecedents.
The main contraindications are the presence of a fetal morphological anomaly and/or high nuchal translucency detected in the first trimester of pregnancy via ultrasound.
In most cases, before undergoing cell-free DNA analysis prenatal screening, the patient must meet with a prenatal diagnosis specialist.
During this consultation, the patient’s personal and family history will be assessed and the risks of fetal abnormality will be discussed using the first trimester ultrasound results as well as the maternal serum marker measurements (free β-HCG and PAPP-A).
Please be sure to bring the following documents to your appointment:
The Fetal Medicine Unit aims to help couples in the analysis, decision-making and monitoring of pregnancy when a fetal malformation or abnormality is detected or suspected or when prenatal diagnosis is being considered due to a family history of genetically transmitted disease.
The Unit is one of 49 centers in France to be certified by the French Agence de la Biomédecine.
The quality and safety of the care we provide undergo a dual evaluation process ensuring our continuous compliance with the highest safety and treatment efficacy standards:
Our specialists use the latest technologies available for prenatal diagnosis:
Schedule an appointment with the Fetal Medicine Unit:
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What you should bring :
For your information : One Day Test Fee information
Fetal Medicine Unit
Aile D - Niveau 1Telephone : + 33 (0)1 46 41 28 82
Make sure you bring your personal ID and your carte vitale if you are covered by French social security (Assurance Maladie)